Polynucleotides



Polynucleotides are a type of injectable biomolecule used to rejuvenate and repair skin. In aesthetic medicine, polynucleotides are often used for skin revitalisation and anti-aging treatments. They are believed to work by stimulating the skin's natural repair processes, promoting collagen and elastin production, improving skin elasticity, and boosting hydration. As polynucleotides help promote the regeneration of tissues and reduce the appearance of wrinkles, they are commonly used in facial treatments to improve skin texture, reduce the appearance of fine lines and restore a youthful glow

What to expect: A loading dose of 2-4 sessions spaced 2-3 weeks apart is required. The number of sessions, will be dependent on individual skin quality, and features. The treatment takes 10-15 minutes, and numbing cream is generally used to reduce discomfort. Pain is mild following the use of numbing cream. Swelling and bruising can occur, but often resolves within 24-72 hours after treatment. Once injected, results should be visible within 4-6 weeks, the product is broken down and absorbed by the skin hence, a single maintenance treatment is repeated every 3-6 months..

Polynucleotides offers a range of benefits

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    Skin Regeneration

    Polynucleotides stimulate the skin’s natural healing process, helping to repair damaged tissue and improve overall skin quality.

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    Improved Hydration

    They enhance the skin’s ability to retain moisture, giving it a plumper, more hydrated look.

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    Boosted Collagen Production:

    By stimulating collagen synthesis, polynucleotides help to reduce the appearance of fine lines and wrinkles.

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    Minimal Downtime

    Treatments are minimally invasive, with little to no recovery time, making them convenient for those with busy lifestyles.

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    Natural and Long-Lasting Results:

    The effects of polynucleotide treatments typically develop over time, providing a gradual and natural improvement in skin texture and tone.

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    Regulation of Inflammatory Response

    Polynucleotides can help modulate the body's inflammatory response by reducing the release of pro-inflammatory cytokines (proteins that promote inflammation). This leads to a decrease in swelling, redness, and irritation in the skin after treatments or due to environmental stressors.

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    Promoting Tissue Repair

    In addition to their ability to reduce inflammation, polynucleotides stimulate the repair and regeneration of damaged tissue, allowing the skin to heal more efficiently. This is particularly beneficial for individuals with skin conditions that involve inflammation, such as acne, rosacea, or post-surgical recovery

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    Soothing and Calming Effects

    When used in aesthetic treatments, polynucleotides help calm the skin, making them ideal for post-procedure care. They can minimize discomfort and the risk of complications like excessive redness or swelling after injections or laser treatments.

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    Prevention of Chronic Inflammation

    Chronic inflammation can accelerate skin aging and lead to a breakdown of collagen. By reducing long-term inflammation, polynucleotides can help protect the skin from premature aging, maintaining its firmness, elasticity, and overall health.

✺ Frequently asked questions ✺

  • Polynucleotides are regenerative treatments derived from DNA fragments that stimulate collagen production, improve skin quality, and support cell repair.

  • Common areas include under the eyes, face, neck, décolletage, and hands—wherever skin needs rejuvenation or hydration.

  • A course of 2 to 4 treatments, spaced 2–4 weeks apart, is typically recommended for optimal results, followed by maintenance sessions.

  • No, polynucleotides are not volumising like dermal fillers. They work on skin quality, texture, and overall regeneration rather than adding volume.

  • Improvements in hydration and skin tone may be seen within weeks, but the full regenerative effects typically develop over 4 to 6 weeks post-treatment